Interactions between therapeutic proteins and acrylic acid leachable
PDA. J. Pharm. Sci. Technol. (2012) 66, 12-19. Liu, D., Nashed-Samuel, Y., Bondarenko, P.V., Brems, D.N., Ren, D.
Protein isoaspartate methyltransferase-mediated 18O-labeling of isoaspartic acid for mass spectrometry analysis
Anal. Chem. (2012) 84, 1056-1062. Liu, M., Cheetham, J., Cauchon, N., Ostovic, J., Ni, W., Ren, D., Zhou, Z.S.
Elucidation of degradants in acidic peak of cation exchange chromatography in an IgG1 monoclonal antibody formed on long-term storage in a liquid formulation
Pharm. Res. (2012) 29, 209-224. Gandhi S., Ren D., Xiao G., Bondarenko P.V., Sloey C., Ricci M.S., Krishnan S.
Detection of trace melamine in raw materials used for protein pharmaceutical manufacturing using surface-enhanced Raman spectroscopy (SERS) with gold nanoparticles
Appl. Spectrosc. (2011) 65, 514-521. Wen, Z.Q., Li, G., Ren, D.
Structure elucidation of highly polar basic degradants by on-line hydrogen/deuterium exchange hydrophilic interaction chromatography coupled to tandem mass spectrometry
J. Chromatogr. A (2010) 1217, 3598-3611. Liu, M., Ronk, M., Ren, D., Ostovic, J., Cauchon, N., Zhou, Z.S., Cheetham, J.
An improved trypsin digestion method minimizes digestion-induced modifications on proteins
Anal. Biochem. (2009) 392, 12-21. Ren, D., Pipes, G.D., Liu, D., Shih, L.Y., Nichols, A.C., Treuheit, M.J., Brems, D.N., Bondarenko, P.V.
Degradation products analysis of an Fc fusion protein using LC/MS methods
Int. J. Biol. Macromol. (2009) 44, 81-85. Ren, D., Ratnaswamy, G., Beierle, J., Treuheit, M.J., Brems, D.N., Bondarenko, P.V.
Top-down N-terminal sequencing of Immunoglobulin subunits with electrospray ionization time of flight mass spectrometry
Anal. Biochem. (2009) 384, 42-48. Ren, D., Pipes, G.D., Hambly, D., Bondarenko, P.V., Treuheit, M.J., Gadgil, H.S.
Structure and stability changes of human IgG1 Fc as a consequence of methionine oxidation
Biochemistry (2008) 47, 5088-5100. Liu, D., Ren, D., Huang, H., Dankberg, J., Rosenfeld, R., Cocco, M.J., Li, L., Brems, D.N., Remmele, R.L.
Reversed-phase liquid chromatography-mass spectrometry of site-specific chemical modifications in intact immunoglobulin molecules and their fragments
J. Chromatogr. A (2008) 1179, 198-204. Ren, D., Pipes, G.D., Xiao, G., Kleemann, G.R., Bondarenko, P.V., Treuheit, M.J., Gadgil, H.S.
Assignment of backbone (1)H, (13)C and (15)N resonances of human IgG1 Fc (51.4 kDa)
Biomol. NMR Assign. (2007) 1, 233-235. Liu, D., Cocco, M.J., Rosenfied, R., Lewis, J. K., Ren, D., Li, L., Remmele, R.L., Brems, D.N.
Reversed-phase liquid chromatography of immunoglobulin G molecules and their fragments with the diphenyl column
J. Chromatogr. A (2007) 1175, 63-68. Ren, D., Pipes, G.D., Hambly, D.M., Bondarenko, P.V., Treuheit, M.J., Brems, D.N., Gadgil, H.S.
Assignment of 1H, 13C and 15N resonances of the reduced human IgG1 C(H)3 domain
Biomol. NMR Assign. (2007) 1, 93-94. Liu, D., Cocco, M.J., Matsumura, M., Ren, D., Becker, B., Remmele, R.L., Brems, D. N.
Screening and sequencing of glycated proteins by neutral loss scan LC/MS/MS method
Anal. Chem. (2007) 79, 5991-5999. Gadgil, H.S., Bondarenko, P.V., Treuheit, M.J., Ren, D.
Structural determinants for the evaporation of intact oligomers from collisionally activated cluster ions
Int. J. Mass Spectrom. (2003) 228, 933-954. Ren D., Polce M.J., Wesdemiotis C.
